| Reaction Details |
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 | Report a problem with these data |
| Target | Major prion protein |
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| Ligand | BDBM66192 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TRFRET-based cell-based high throughput dose response assay to identify inhibitors of cell surface Prion Protein (PRPC) |
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| IC50 | 1410±n/a nM |
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| Citation |  PubChem, PC TRFRET-based cell-based high throughput dose response assay to identify inhibitors of cell surface Prion Protein (PRPC) PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Major prion protein |
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| Name: | Major prion protein |
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| Synonyms: | ALTPRP | ASCR | CD_antigen=CD230 | PRIO_HUMAN | PRIP | PRNP | PRP | PrP27-30 | PrP33-35C | Prion protein | major prion protein preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27671.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_158887 |
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| Residue: | 253 |
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| Sequence: | MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
ILLISFLIFLIVG
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| BDBM66192 |
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| n/a |
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| Name | BDBM66192 |
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| Synonyms: | 6-bromanyl-2-thiophen-2-yl-quinoline-4-carboxylic acid | 6-bromo-2-(2-thienyl)cinchoninic acid | 6-bromo-2-thiophen-2-yl-4-quinolinecarboxylic acid | 6-bromo-2-thiophen-2-ylquinoline-4-carboxylic acid | MLS001182077 | SMR000567820 | cid_755656 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H8BrNO2S |
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| Mol. Mass. | 334.188 |
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| SMILES | OC(=O)c1cc(nc2ccc(Br)cc12)-c1cccs1 |
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| Structure | 
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