BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Target5-hydroxytryptamine receptor 2A
LigandBDBM114608
Substrate/Competitorn/a
Meas. Tech.Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50 76083±n/a nM
Citation PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
5-hydroxytryptamine receptor 2A
Name:5-hydroxytryptamine receptor 2A
Synonyms:5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor
Type:Enzyme
Mol. Mass.:52843.00
Organism:Mus musculus (Mouse)
Description:P35363
Residue:471
Sequence:
MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM114608
n/a
NameBDBM114608
Synonyms:1-(4-benzoxybenzyl)-4-(2-pyridyl)piperazine | 1-[(4-phenylmethoxyphenyl)methyl]-4-(2-pyridinyl)piperazine | 1-[(4-phenylmethoxyphenyl)methyl]-4-pyridin-2-yl-piperazine | 1-[(4-phenylmethoxyphenyl)methyl]-4-pyridin-2-ylpiperazine | SR-01000676885 | SR-01000676885-2 | cid_1377542
TypeSmall organic molecule
Emp. Form.C23H25N3O
Mol. Mass.359.4641
SMILESC(Oc1ccc(CN2CCN(CC2)c2ccccn2)cc1)c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: