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Target5-hydroxytryptamine receptor 2A
LigandBDBM38732
Substrate/Competitorn/a
Meas. Tech.Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50 76083±n/a nM
Citation PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
5-hydroxytryptamine receptor 2A
Name:5-hydroxytryptamine receptor 2A
Synonyms:5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor
Type:Enzyme
Mol. Mass.:52843.00
Organism:Mus musculus (Mouse)
Description:P35363
Residue:471
Sequence:
MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
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  Blast E-value cutoff:
BDBM38732
n/a
NameBDBM38732
Synonyms:2-furanyl-[4-[(4-methoxy-3-phenylmethoxyphenyl)methyl]-1-piperazinyl]methanone | MLS000108279 | SMR000104240 | [4-(3-benzoxy-4-methoxy-benzyl)piperazino]-(2-furyl)methanone | cid_1148134 | furan-2-yl-[4-[(4-methoxy-3-phenylmethoxy-phenyl)methyl]piperazin-1-yl]methanone | furan-2-yl-[4-[(4-methoxy-3-phenylmethoxyphenyl)methyl]piperazin-1-yl]methanone
TypeSmall organic molecule
Emp. Form.C24H26N2O4
Mol. Mass.406.4742
SMILESCOc1ccc(CN2CCN(CC2)C(=O)c2ccco2)cc1OCc1ccccc1
Structure
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