Reaction Details |
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Target | 5-hydroxytryptamine receptor 2A |
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Ligand | BDBM114614 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) |
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EC50 | 76083±n/a nM |
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Citation | PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay(2013)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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5-hydroxytryptamine receptor 2A |
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Name: | 5-hydroxytryptamine receptor 2A |
Synonyms: | 5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor |
Type: | Enzyme |
Mol. Mass.: | 52843.00 |
Organism: | Mus musculus (Mouse) |
Description: | P35363 |
Residue: | 471 |
Sequence: | MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
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BDBM114614 |
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n/a |
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Name | BDBM114614 |
Synonyms: | (4-benzylpiperazin-1-yl)-[3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropyl]methanone | (4-benzylpiperazino)-[3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropyl]methanone | SR-01000259344 | SR-01000259344-3 | [3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropyl]-[4-(phenylmethyl)-1-piperazinyl]methanone | [3-[2,2-bis(chloranyl)ethenyl]-2,2-dimethyl-cyclopropyl]-[4-(phenylmethyl)piperazin-1-yl]methanone | cid_2935972 |
Type | Small organic molecule |
Emp. Form. | C19H24Cl2N2O |
Mol. Mass. | 367.313 |
SMILES | [#6]C1([#6])[#6](\[#6]=[#6](\Cl)Cl)-[#6]1-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-c2ccccc2)-[#6]-[#6]-1 |
Structure |
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