| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM72487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) |
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| EC50 | 76083±n/a nM |
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| Citation |  PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 52843.00 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P35363 |
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| Residue: | 471 |
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| Sequence: | MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
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| BDBM72487 |
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| n/a |
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| Name | BDBM72487 |
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| Synonyms: | MLS000733547 | SMR000316874 | [1-(1-benzofuran-2-ylmethyl)-4-[[3-(trifluoromethyl)phenyl]methyl]piperidin-4-yl]methanol | [1-(2-benzofuranylmethyl)-4-[[3-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methanol | [1-(benzofuran-2-ylmethyl)-4-[3-(trifluoromethyl)benzyl]-4-piperidyl]methanol | cid_16191594 | {1-(1-benzofuran-2-ylmethyl)-4-[3-(trifluoromethyl)benzyl]piperidin-4-yl}methanol |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24F3NO2 |
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| Mol. Mass. | 403.4374 |
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| SMILES | OCC1(Cc2cccc(c2)C(F)(F)F)CCN(Cc2cc3ccccc3o2)CC1 |
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| Structure | 
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