Reaction Details |
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Target | 5-hydroxytryptamine receptor 2A |
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Ligand | BDBM114625 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) |
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EC50 | 76083±n/a nM |
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Citation | PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay(2013)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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5-hydroxytryptamine receptor 2A |
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Name: | 5-hydroxytryptamine receptor 2A |
Synonyms: | 5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor |
Type: | Enzyme |
Mol. Mass.: | 52843.00 |
Organism: | Mus musculus (Mouse) |
Description: | P35363 |
Residue: | 471 |
Sequence: | MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
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BDBM114625 |
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n/a |
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Name | BDBM114625 |
Synonyms: | 2-[4-(4-methoxy-2,3-dimethyl-benzyl)piperazino]pyrimidine | 2-[4-[(4-methoxy-2,3-dimethyl-phenyl)methyl]piperazin-1-yl]pyrimidine | 2-[4-[(4-methoxy-2,3-dimethylphenyl)methyl]-1-piperazinyl]pyrimidine | 2-[4-[(4-methoxy-2,3-dimethylphenyl)methyl]piperazin-1-yl]pyrimidine | SR-01000201524 | SR-01000201524-3 | cid_791369 |
Type | Small organic molecule |
Emp. Form. | C18H24N4O |
Mol. Mass. | 312.4094 |
SMILES | COc1ccc(CN2CCN(CC2)c2ncccn2)c(C)c1C |
Structure |
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