| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM76106 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) |
|---|
| EC50 | 3467±n/a nM |
|---|
| Citation |  PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52843.00 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P35363 |
|---|
| Residue: | 471 |
|---|
| Sequence: | MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
|
|
|
|---|
| BDBM76106 |
|---|
| n/a |
|---|
| Name | BDBM76106 |
|---|
| Synonyms: | 6-(1-benzimidazolylmethyl)-4-(2,5-dimethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid methyl ester | 6-(benzimidazol-1-ylmethyl)-4-(2,5-dimethylphenyl)-2-keto-3,4-dihydro-1H-pyrimidine-5-carboxylic acid methyl ester | MLS000052786 | SMR000082609 | cid_2983279 | methyl 6-(1H-benzimidazol-1-ylmethyl)-4-(2,5-dimethylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate | methyl 6-(benzimidazol-1-ylmethyl)-4-(2,5-dimethylphenyl)-2-oxidanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate | methyl 6-(benzimidazol-1-ylmethyl)-4-(2,5-dimethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H22N4O3 |
|---|
| Mol. Mass. | 390.4351 |
|---|
| SMILES | COC(=O)C1C(NC(=O)N=C1Cn1cnc2ccccc12)c1cc(C)ccc1C |c:9| |
|---|
| Structure | 
|
|---|
Search and Browse
