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Target5-hydroxytryptamine receptor 2A
LigandBDBM38726
Substrate/Competitorn/a
Meas. Tech.Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50 76083±n/a nM
Citation PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
5-hydroxytryptamine receptor 2A
Name:5-hydroxytryptamine receptor 2A
Synonyms:5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor
Type:Enzyme
Mol. Mass.:52843.00
Organism:Mus musculus (Mouse)
Description:P35363
Residue:471
Sequence:
MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
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  Blast E-value cutoff:
BDBM38726
n/a
NameBDBM38726
Synonyms:2-[4-(3-fluorobenzyl)piperazino]pyrimidine | 2-[4-[(3-fluorophenyl)methyl]-1-piperazinyl]pyrimidine | 2-[4-[(3-fluorophenyl)methyl]piperazin-1-yl]pyrimidine | MLS000105283 | SMR000102164 | cid_763417
TypeSmall organic molecule
Emp. Form.C15H17FN4
Mol. Mass.272.3207
SMILESFc1cccc(CN2CCN(CC2)c2ncccn2)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: