| Reaction Details |
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 | Report a problem with these data |
| Target | Fibrinogen beta chain [164-491] |
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| Ligand | BDBM94217 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer |
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| IC50 | 10587±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Fibrinogen beta chain [164-491] |
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| Name: | Fibrinogen beta chain [164-491] |
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| Synonyms: | Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37647.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_28373962 |
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| Residue: | 328 |
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| Sequence: | DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
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| BDBM94217 |
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| n/a |
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| Name | BDBM94217 |
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| Synonyms: | MLS000529731 | N-[(1,2-dimethyl-5-indolyl)methyl]-4-(4-morpholinylsulfonyl)benzamide | N-[(1,2-dimethylindol-5-yl)methyl]-4-morpholin-4-ylsulfonyl-benzamide | N-[(1,2-dimethylindol-5-yl)methyl]-4-morpholin-4-ylsulfonylbenzamide | N-[(1,2-dimethylindol-5-yl)methyl]-4-morpholinosulfonyl-benzamide | SMR000127186 | cid_3251511 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25N3O4S |
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| Mol. Mass. | 427.517 |
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| SMILES | Cc1cc2cc(CNC(=O)c3ccc(cc3)S(=O)(=O)N3CCOCC3)ccc2n1C |
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| Structure | 
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