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TargetFibrinogen beta chain [164-491]
LigandBDBM114662
Substrate/Competitorn/a
Meas. Tech.Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer
IC50 83135±n/a nM
Citation PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Fibrinogen beta chain [164-491]
Name:Fibrinogen beta chain [164-491]
Synonyms:Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN
Type:Enzyme Catalytic Domain
Mol. Mass.:37647.12
Organism:Homo sapiens (Human)
Description:gi_28373962
Residue:328
Sequence:
DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM114662
n/a
NameBDBM114662
Synonyms:4-(prop-2-ynylamino)benzoic acid ethyl ester | 4-(propargylamino)benzoic acid ethyl ester | MLS000756461 | SMR000528743 | cid_305814 | ethyl 4-(prop-2-ynylamino)benzoate
TypeSmall organic molecule
Emp. Form.C12H13NO2
Mol. Mass.203.2371
SMILESCCOC(=O)c1ccc(NCC#C)cc1
Structure
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