| Reaction Details |
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 | Report a problem with these data |
| Target | Fibrinogen beta chain [164-491] |
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| Ligand | BDBM52976 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer |
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| IC50 | 16011±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Fibrinogen beta chain [164-491] |
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| Name: | Fibrinogen beta chain [164-491] |
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| Synonyms: | Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37647.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_28373962 |
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| Residue: | 328 |
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| Sequence: | DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
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| BDBM52976 |
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| n/a |
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| Name | BDBM52976 |
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| Synonyms: | (3-cyclopropyl-7-methyl-6,8-dioxoisochromen-7-yl) furan-2-carboxylate | 2-furancarboxylic acid (3-cyclopropyl-7-methyl-6,8-dioxo-2-benzopyran-7-yl) ester | CMLD003316 | MLS000438874 | SMR000452580 | [3-cyclopropyl-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] furan-2-carboxylate | cid_16759460 | furan-2-carboxylic acid (3-cyclopropyl-6,8-diketo-7-methyl-isochromen-7-yl) ester |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14O6 |
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| Mol. Mass. | 326.3002 |
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| SMILES | CC1(OC(=O)c2ccco2)C(=O)C=C2C=C(OC=C2C1=O)C1CC1 |c:15,18,t:13| |
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| Structure | 
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