| Reaction Details |
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 | Report a problem with these data |
| Target | Protein artemis |
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| Ligand | BDBM66045 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule inhibitors originally identified via uHTS of Artemis endonuclease activity via a fluorescence intensity assay |
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| IC50 | 11000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule inhibitors originally identified via uHTS of Artemis endonuclease activity via a fluorescence intensity assay PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Protein artemis |
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| Name: | Protein artemis |
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| Synonyms: | ARTEMIS | ASCID | DCLRE1C | DCR1C_HUMAN | SCIDA | SNM1C | protein artemis isoform a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 78427.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_76496497 |
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| Residue: | 692 |
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| Sequence: | MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLY
CSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSV
MFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSRE
ECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPE
ILHHLTTDRNTQIHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRK
TNVIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGTTMDKVVEILKPLCR
SSQSTEPKYKPLGKLKRARTVHRDSEEEDDYLFDDPLPIPLRHKVPYPETFHPEVFSMTA
VSEKQPEKLRQTPGCCRAECMQSSRFTNFVDCEESNSESEEEVGIPASLQGDLGSVLHLQ
KADGDVPQWEVFFKRNDEITDESLENFPSSTVAGGSQSPKLFSDSDGESTHISSQNSSQS
THITEQGSQGWDSQSDTVLLSSQERNSGDITSLDKADYRPTIKENIPASLMEQNVICPKD
TYSDLKSRDKDVTIVPSTGEPTTLSSETHIPEEKSLLNLSTNADSQSSSDFEVPSTPEAE
LPKREHLQYLYEKLATGESIAVKKRKCSLLDT
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| BDBM66045 |
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| n/a |
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| Name | BDBM66045 |
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| Synonyms: | (2E)-2-(1-nitrosodecylidene)-1H-pyridine | 1-Pyridin-2-yl-decan-1-one oxime | MLS000555881 | SMR000147398 | cid_5937406 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N2O |
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| Mol. Mass. | 248.3639 |
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| SMILES | CCCCCCCCCC(N=O)c1ccccn1 |
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| Structure | 
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