Ki Summary

Reaction Details

Report a problem with these data

Target

Tegument protein VP16

Ligand

BDBM3256

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16)

IC50

85346±n/a nM

Citation

PubChem, PC Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2013)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Tegument protein VP16

Name:

Tegument protein VP16

Synonyms:

Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16

Type:

PROTEIN

Mol. Mass.:

54325.13

Organism:

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)

Description:

EBI_100271

Residue:

490

Sequence:

MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG

BDBM3256

n/a

Name

BDBM3256

Synonyms:

4-(Benzylamino)quinazoline deriv. 7 | N-benzylquinazolin-4-amine | benzyl(quinazolin-4-yl)amine;hydrochloride | cid_616573

Type

Small organic molecule

Emp. Form.

C15H13N3

Mol. Mass.

235.2838

SMILES

C(Nc1ncnc2ccccc12)c1ccccc1

Structure