| Reaction Details |
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 | Report a problem with these data |
| Target | Tegument protein VP16 |
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| Ligand | BDBM100198 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) |
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| IC50 | 21333±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tegument protein VP16 |
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| Name: | Tegument protein VP16 |
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| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54325.13 |
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| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
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| Description: | EBI_100271 |
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| Residue: | 490 |
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| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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| BDBM100198 |
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| n/a |
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| Name | BDBM100198 |
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| Synonyms: | (4Z)-5-(2-furanyl)-4-[hydroxy-(5-methyl-1-phenyl-4-pyrazolyl)methylidene]-1-[2-(4-morpholinyl)ethyl]pyrrolidine-2,3-dione | (4Z)-5-(2-furyl)-4-[hydroxy-(5-methyl-1-phenyl-pyrazol-4-yl)methylene]-1-(2-morpholinoethyl)pyrrolidine-2,3-quinone | (4Z)-5-(furan-2-yl)-4-[(5-methyl-1-phenyl-pyrazol-4-yl)-oxidanyl-methylidene]-1-(2-morpholin-4-ylethyl)pyrrolidine-2,3-dione | (4Z)-5-(furan-2-yl)-4-[hydroxy-(5-methyl-1-phenylpyrazol-4-yl)methylidene]-1-(2-morpholin-4-ylethyl)pyrrolidine-2,3-dione | MLS000077939 | SMR000041809 | cid_5389306 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H26N4O5 |
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| Mol. Mass. | 462.4977 |
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| SMILES | Cc1c(cnn1-c1ccccc1)C(=O)C1C(N(CCN2CCOCC2)C(=O)C1=O)c1ccco1 |
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| Structure | 
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