| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear hormone receptor family member daf-12 |
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| Ligand | BDBM45062 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) |
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| IC50 | 67499±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nuclear hormone receptor family member daf-12 |
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| Name: | Nuclear hormone receptor family member daf-12 |
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| Synonyms: | DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 84211.49 |
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| Organism: | Caenorhabditis elegans |
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| Description: | gi_71987181 |
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| Residue: | 753 |
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| Sequence: | MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQM
STPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRV
CGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFT
VGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYP
PQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLT
MMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLM
NEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIP
GNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAM
IPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQ
MQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGV
TRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAV
YLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALG
LLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
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| BDBM45062 |
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| n/a |
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| Name | BDBM45062 |
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| Synonyms: | (6E)-3-methyl-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one | (6Z)-3-methyl-6-(3-phenyl-2H-1,2-oxazol-5-ylidene)cyclohexa-2,4-dien-1-one | (6Z)-3-methyl-6-(3-phenyl-2H-isoxazol-5-ylidene)-1-cyclohexa-2,4-dienone | (6Z)-3-methyl-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one | 5-methyl-2-(3-phenyl-5-isoxazolyl)phenol | MLS000583415 | SMR000193314 | cid_5414842 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13NO2 |
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| Mol. Mass. | 251.2799 |
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| SMILES | Cc1ccc(-c2cc(no2)-c2ccccc2)c(O)c1 |
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| Structure | 
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