| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxysterols receptor LXR-beta |
|---|
| Ligand | BDBM49423 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR) |
|---|
| EC50 | 67529±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR) PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Oxysterols receptor LXR-beta |
|---|
| Name: | Oxysterols receptor LXR-beta |
|---|
| Synonyms: | LXRB | Liver X receptor beta (NR1H2) | Liver X, LXR beta | NER | NR1H2 | NR1H2_HUMAN | Nuclear receptor NER | UNR | Ubiquitously-expressed nuclear receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50978.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P55055 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQ
SQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKR
SFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQI
ALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMR
RLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRM
LMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
|
|
|
|---|
| BDBM49423 |
|---|
| n/a |
|---|
| Name | BDBM49423 |
|---|
| Synonyms: | (E)-3-(3,4-dimethylanilino)-2-(3-thienyl)acrylonitrile | (E)-3-(3,4-dimethylanilino)-2-(3-thiophenyl)-2-propenenitrile | (E)-3-(3,4-dimethylanilino)-2-thiophen-3-ylprop-2-enenitrile | (E)-3-[(3,4-dimethylphenyl)amino]-2-thiophen-3-yl-prop-2-enenitrile | MLS000539447 | SMR000125105 | cid_2766393 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H14N2S |
|---|
| Mol. Mass. | 254.35 |
|---|
| SMILES | Cc1ccc(cc1C)N=CC(C#N)c1ccsc1 |w:8.8| |
|---|
| Structure | 
|
|---|
Search and Browse
