| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxysterols receptor LXR-beta |
|---|
| Ligand | BDBM114998 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR) |
|---|
| EC50 | 67554±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR) PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Oxysterols receptor LXR-beta |
|---|
| Name: | Oxysterols receptor LXR-beta |
|---|
| Synonyms: | LXRB | Liver X receptor beta (NR1H2) | Liver X, LXR beta | NER | NR1H2 | NR1H2_HUMAN | Nuclear receptor NER | UNR | Ubiquitously-expressed nuclear receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50978.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P55055 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQ
SQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKR
SFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQI
ALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMR
RLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRM
LMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
|
|
|
|---|
| BDBM114998 |
|---|
| n/a |
|---|
| Name | BDBM114998 |
|---|
| Synonyms: | 6-(4-bromanyl-3,5-dimethyl-pyrazol-1-yl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine | 6-(4-bromo-3,5-dimethyl-1-pyrazolyl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine | 6-(4-bromo-3,5-dimethylpyrazol-1-yl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine | MLS000702666 | N-[6-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetraazin-3-yl]-N-cyclohexylamine | SMR000225861 | [6-(4-bromo-3,5-dimethyl-pyrazol-1-yl)-1,2,4,5-tetrazin-3-yl]-cyclohexyl-amine | cid_5113181 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H18BrN7 |
|---|
| Mol. Mass. | 352.233 |
|---|
| SMILES | Cc1nn(c(C)c1Br)-c1nnc(NC2CCCCC2)nn1 |
|---|
| Structure | 
|
|---|
Search and Browse
