| Reaction Details |
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 | Report a problem with these data |
| Target | Oxysterols receptor LXR-beta |
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| Ligand | BDBM49089 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR) |
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| EC50 | 67547±n/a nM |
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| Citation |  PubChem, PC Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR) PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Oxysterols receptor LXR-beta |
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| Name: | Oxysterols receptor LXR-beta |
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| Synonyms: | LXRB | Liver X receptor beta (NR1H2) | Liver X, LXR beta | NER | NR1H2 | NR1H2_HUMAN | Nuclear receptor NER | UNR | Ubiquitously-expressed nuclear receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50978.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55055 |
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| Residue: | 460 |
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| Sequence: | MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQ
SQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKR
SFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQI
ALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMR
RLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRM
LMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
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| BDBM49089 |
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| n/a |
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| Name | BDBM49089 |
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| Synonyms: | 2-(2-furoylimino)-5-keto-1-propyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylic acid ethyl ester | 2-[2-furanyl(oxo)methyl]imino-5-oxo-1-propyl-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxylic acid ethyl ester | MLS000052096 | SMR000081413 | cid_1251509 | ethyl 2-(2-furoylimino)-5-oxo-1-propyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate | ethyl 2-(furan-2-carbonylimino)-5-oxo-1-propyldipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylate | ethyl 2-(furan-2-ylcarbonylimino)-5-oxidanylidene-1-propyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N4O5 |
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| Mol. Mass. | 420.418 |
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| SMILES | CCCn1c2nc3ccccn3c(=O)c2cc(C(=O)OCC)\c1=N/C(=O)c1ccco1 |
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| Structure | 
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