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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | PC4 and SFRS1-interacting protein | ||
| Ligand | BDBM37534 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization | ||
| IC50 | 2533±n/a nM | ||
| Citation |  PubChem, PC Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization PubChem Bioassay(2014)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| PC4 and SFRS1-interacting protein | |||
| Name: | PC4 and SFRS1-interacting protein | ||
| Synonyms: | DFS70 | LEDGF | LEDGF/p75 | PSIP1 | PSIP1_HUMAN | PSIP2 | lens epithelium-derived growth factor p75 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 60120.68 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_6708281 | ||
| Residue: | 530 | ||
| Sequence: |
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| BDBM37534 | |||
| n/a | |||
| Name | BDBM37534 | ||
| Synonyms: | (2E,4R,12aR)-2-[amino(hydroxy)methylene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride | (2E,4R,12aR)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride | (2E,4R,12aR)-2-[azanyl(oxidanyl)methylidene]-4,7-bis(dimethylamino)-10,11,12a-tris(oxidanyl)-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione;hydrochloride | (4R,12aS)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-diketo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride | MINOCYCLINE HYDROCHLORIDE | MLS000028367 | SMR000058620 | cid_6602603 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H27N3O7 | ||
| Mol. Mass. | 457.4764 | ||
| SMILES | CN(C)[C@@H]1C2CC3Cc4c(ccc(O)c4C(=O)C3C(=O)[C@@]2(O)C(=O)C(C(N)=O)C1=O)N(C)C | ||
| Structure | 
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