| Reaction Details |
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 | Report a problem with these data |
| Target | PC4 and SFRS1-interacting protein |
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| Ligand | BDBM60915 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization |
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| IC50 | 2654±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| PC4 and SFRS1-interacting protein |
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| Name: | PC4 and SFRS1-interacting protein |
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| Synonyms: | DFS70 | LEDGF | LEDGF/p75 | PSIP1 | PSIP1_HUMAN | PSIP2 | lens epithelium-derived growth factor p75 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60120.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_6708281 |
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| Residue: | 530 |
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| Sequence: | MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
NMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIK
NSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLY
NKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNG
GSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN
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| BDBM60915 |
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| n/a |
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| Name | BDBM60915 |
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| Synonyms: | (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(5-quinolinyl)-2-propenamide | (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(5-quinolyl)acrylamide | (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-quinolin-5-ylprop-2-enamide | (E)-3-[3,4-bis(oxidanyl)phenyl]-2-cyano-N-quinolin-5-yl-prop-2-enamide | MLS001173932 | SMR000591923 | cid_9114427 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H13N3O3 |
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| Mol. Mass. | 331.3248 |
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| SMILES | Oc1ccc(\C=C(/C#N)C(=O)Nc2cccc3ncccc23)cc1O |
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| Structure | 
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