Reaction Details |
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Target | PC4 and SFRS1-interacting protein |
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Ligand | BDBM80747 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization |
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IC50 | 953±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization PubChem Bioassay(2014)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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PC4 and SFRS1-interacting protein |
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Name: | PC4 and SFRS1-interacting protein |
Synonyms: | DFS70 | LEDGF | LEDGF/p75 | PSIP1 | PSIP1_HUMAN | PSIP2 | lens epithelium-derived growth factor p75 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 60120.68 |
Organism: | Homo sapiens (Human) |
Description: | gi_6708281 |
Residue: | 530 |
Sequence: | MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
NMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIK
NSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLY
NKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNG
GSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN
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BDBM80747 |
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n/a |
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Name | BDBM80747 |
Synonyms: | 4-oxidanyl-6-phenylazanyl-naphthalene-1-sulfonic acid | 6-anilino-4-hydroxy-1-naphthalenesulfonic acid | 6-anilino-4-hydroxy-naphthalene-1-sulfonic acid | 6-anilino-4-hydroxynaphthalene-1-sulfonic acid | MLS002637586 | SMR001547116 | cid_219926 |
Type | Small organic molecule |
Emp. Form. | C16H13NO4S |
Mol. Mass. | 315.344 |
SMILES | Oc1ccc(c2ccc(Nc3ccccc3)cc12)S(O)(=O)=O |
Structure |
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