| Reaction Details |
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 | Report a problem with these data |
| Target | PC4 and SFRS1-interacting protein |
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| Ligand | BDBM84370 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization |
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| IC50 | 1351±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| PC4 and SFRS1-interacting protein |
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| Name: | PC4 and SFRS1-interacting protein |
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| Synonyms: | DFS70 | LEDGF | LEDGF/p75 | PSIP1 | PSIP1_HUMAN | PSIP2 | lens epithelium-derived growth factor p75 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60120.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_6708281 |
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| Residue: | 530 |
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| Sequence: | MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
NMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIK
NSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLY
NKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNG
GSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN
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| BDBM84370 |
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| n/a |
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| Name | BDBM84370 |
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| Synonyms: | 6-bromanyl-7-[4-[2-(2-hydroxyethyloxy)ethyl]piperazin-1-yl]-5,8-bis(oxidanyl)naphthalene-1,4-dione;hydrochloride | 6-bromo-5,8-dihydroxy-7-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]naphthalene-1,4-dione;hydrochloride | 6-bromo-5,8-dihydroxy-7-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]naphthalene-1,4-dione;hydrochloride | 6-bromo-5,8-dihydroxy-7-[4-[2-(2-hydroxyethoxy)ethyl]piperazino]-1,4-naphthoquinone;hydrochloride | MLS002701606 | SMR001565207 | cid_378196 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21BrN2O6 |
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| Mol. Mass. | 441.273 |
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| SMILES | OCCOCCN1CCN(CC1)c1c(O)c2C(=O)C=CC(=O)c2c(O)c1Br |c:19| |
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| Structure | 
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