Ki Summary

Reaction Details

Report a problem with these data

Target

D(3) dopamine receptor

Ligand

BDBM121512

Substrate/Competitor

n/a

Meas. Tech.

Radioligand Binding Assay

3.55±n/a nM

Citation

Rodriguez Sarmiento, RM; Wichmann, J Benzodioxole piperazine compounds US Patent US8722683 Publication Date 5/13/2014

More Info.:

Get all data from this article, Assay Method

D(3) dopamine receptor

Name:

D(3) dopamine receptor

Synonyms:

Type:

n/a

Mol. Mass.:

44243.43

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

400

Sequence:

MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC

BDBM121512

n/a

Name

BDBM121512

Synonyms:

US8722683, 59

Type

Small organic molecule

Emp. Form.

C27H32N4O3

Mol. Mass.

460.568

SMILES

O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1)c1ccc(cc1)C#N |r,wU:3.2,wD:6.6,(3.85,-.82,;4.62,.52,;3.85,1.85,;2.31,1.85,;1.54,.52,;,.52,;-.77,1.85,;-2.31,1.85,;-3.08,.52,;-4.62,.52,;-5.39,-.82,;-6.93,-.82,;-7.7,.52,;-6.93,1.85,;-5.39,1.85,;-9.24,.52,;-10.01,1.85,;-11.55,1.85,;-12.32,.52,;-11.55,-.82,;-12.03,-2.28,;-10.78,-3.19,;-9.53,-2.28,;-10.01,-.82,;,3.19,;1.54,3.19,;6.16,.52,;6.93,1.85,;8.47,1.85,;9.24,.52,;8.47,-.82,;6.93,-.82,;10.78,.52,;12.32,.52,)|

Structure