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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Insulin-like growth factor 1 receptor | ||
| Ligand | BDBM122713 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | DELFIA assay | ||
| pH | 7.4±n/a | ||
| IC50 | 0.7±n/a nM | ||
| Comments | extracted | ||
| Citation |  Treu, M Aminopyrazoloquinazolines US Patent US8735386 Publication Date 5/27/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Insulin-like growth factor 1 receptor | |||
| Name: | Insulin-like growth factor 1 receptor | ||
| Synonyms: | CD_antigen=CD221 | IGF-I receptor | IGF1R | IGF1R_HUMAN | Insulin-like growth factor 1 receptor (IGF1R) | Insulin-like growth factor 1 receptor (IGFIR) | Insulin-like growth factor 1 receptor alpha chain | Insulin-like growth factor 1 receptor beta chain | Insulin-like growth factor I receptor | Insulin-like growth factor receptor (IGFR) | ||
| Type: | Protein | ||
| Mol. Mass.: | 154776.79 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P08069 | ||
| Residue: | 1367 | ||
| Sequence: |
| ||
| BDBM122713 | |||
| n/a | |||
| Name | BDBM122713 | ||
| Synonyms: | US8735386, I-183 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H20ClN7OS | ||
| Mol. Mass. | 441.937 | ||
| SMILES | COCCn1cc(Nc2ncc3CCc4nn(C)c(-c5sccc5Cl)c4-c3n2)cn1 |(-8.14,4.59,;-7.37,3.25,;-5.83,3.25,;-5.06,1.92,;-3.52,1.92,;-2.61,.67,;-1.15,1.15,;.18,.38,;1.52,1.15,;1.52,2.69,;2.85,3.46,;4.18,2.69,;5.52,3.46,;6.85,2.69,;6.85,1.15,;8,.12,;7.37,-1.29,;8.14,-2.62,;5.84,-1.13,;4.75,-2.22,;5.23,-3.68,;3.98,-4.59,;2.73,-3.68,;3.21,-2.22,;2.44,-.88,;5.52,.38,;4.18,1.15,;2.85,.38,;-1.15,2.69,;-2.61,3.16,)| | ||
| Structure | 
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