| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 2 |
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| Ligand | BDBM124252 |
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| Substrate/Competitor | n/a |
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| IC50 | 1.316e+4± 5.1e+2 nM |
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| Citation |  Yin, JP; Tang, CL; Gao, LX; Ma, WP; Li, JY; Li, Y; Li, J; Nan, FJ Design and synthesis of paracaseolide A analogues as selective protein tyrosine phosphatase 1B inhibitors. Org Biomol Chem12:3441-5 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Tyrosine-protein phosphatase non-receptor type 2 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 2 |
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| Synonyms: | PTN2_HUMAN | PTPN2 | PTPT | T-cell protein tyrosine phosphatase (TCPTP) | T-cell protein-tyrosine phosphatase | TC-PTP | TCPTP | Tyrosine-protein phosphatase non-receptor type 2 | Tyrosine-protein phosphatase non-receptor type 2 (TC-PTP) |
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| Type: | Protein |
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| Mol. Mass.: | 48481.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P17706 |
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| Residue: | 415 |
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| Sequence: | MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
TAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
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| BDBM124252 |
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| n/a |
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| Name | BDBM124252 |
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| Synonyms: | (1R,2S,3S,8R,9S,12S)-8-dodecyl-3,12-dimethyl-9-[(1E)-tetradec-1-en-1-yl]-4,11-dioxatricyclo[7.3.0.0,⁶]dodec-6-ene-5,10-dione (6) |
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| Type | Small organic molecule |
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| Emp. Form. | C38H64O4 |
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| Mol. Mass. | 584.9124 |
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| SMILES | CCCCCCCCCCCC\C=C\[C@]12[C@H]([C@H](C)OC1=O)[C@@H]1[C@H](C)OC(=O)C1=C[C@H]2CCCCCCCCCCCC |r,c:29| |
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| Structure | 
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