| Reaction Details |
|---|
 | Report a problem with these data |
| Target | M-phase inducer phosphatase 2 |
|---|
| Ligand | BDBM124253 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 3.93e+3± 1.7e+2 nM |
|---|
| Citation |  Yin, JP; Tang, CL; Gao, LX; Ma, WP; Li, JY; Li, Y; Li, J; Nan, FJ Design and synthesis of paracaseolide A analogues as selective protein tyrosine phosphatase 1B inhibitors. Org Biomol Chem12:3441-5 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| M-phase inducer phosphatase 2 |
|---|
| Name: | M-phase inducer phosphatase 2 |
|---|
| Synonyms: | CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 64985.27 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 580 |
|---|
| Sequence: | MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMH
DLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMD
PHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEA
GSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPD
RKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT
LEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQ
QEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETM
VALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKR
VILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQ
DYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
|
|
|
|---|
| BDBM124253 |
|---|
| n/a |
|---|
| Name | BDBM124253 |
|---|
| Synonyms: | (1R,2S,3S,8R,9S,12S)-8-dodecyl-3,12-dimethyl-9-[(1E)-pentadec-1-en-1-yl]-4,11-dioxatricyclo[7.3.0.0,⁶]dodec-6-ene-5,10-dione (7) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C39H66O4 |
|---|
| Mol. Mass. | 598.9389 |
|---|
| SMILES | CCCCCCCCCCCCC\C=C\[C@]12[C@H]([C@H](C)OC1=O)[C@@H]1[C@H](C)OC(=O)C1=CC2CCCCCCCCCCCC |r,c:30| |
|---|
| Structure | 
|
|---|
Search and Browse
