| Reaction Details |
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 | Report a problem with these data |
| Target | RNA-editing ligase 1, mitochondrial |
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| Ligand | BDBM128146 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Trypanosoma brucei RNA editing ligase 1 (TbREL1). |
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| IC50 | 12331±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Trypanosoma brucei RNA editing ligase 1 (TbREL1). PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| RNA-editing ligase 1, mitochondrial |
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| Name: | RNA-editing ligase 1, mitochondrial |
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| Synonyms: | REL1 | RLGM1_TRYBB | Trypanosoma brucei RNA editing ligase 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52299.36 |
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| Organism: | Trypanosoma brucei brucei |
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| Description: | gi_342179211 |
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| Residue: | 469 |
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| Sequence: | MQLQRLGAPLLKRLVGGCIRQSTAPIMPCVVVSGSGVFLTPVRTYMPLPNDQSDFSPYIE
IDLPSESRIQSLHKSGLAAQEWVACEKVHGTNFGIYLINQGDHEVVRFAKRSGIMDPNEN
FFGYHILIDEFTAQIRILNDLLKQKYGLSRVGRLVLNGELFGAKYKHPLVPKSEKWCTLP
NGKKFPIAGVQIQREPFPQYSPELHFFAFDIKYSVSGAEEDFVLLGYDEFVEFSSKVPNL
LYARALVRGTLDECLAFDVENFMTPLPALLGLGNYPLEGNLAEGVVIRHVRRGDPAVEKH
NVSTIIKLRCSSFMELKHPGKQKELKETFIDTVRSGALRRVRGNVTVISDSMLPQVEAAA
NDLLLNNVSDGRLSNVLSKIGREPLLSGEVSQVDVVLMLAKDALKDFLKEVDSLVLNTTL
AFRKLLITNVYFESKRLVEQKWKELMQEEAAAQSEAIPPLSPAAPTKGE
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| BDBM128146 |
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| n/a |
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| Name | BDBM128146 |
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| Synonyms: | 3,5-bis(2,5-dioxo-1-pyrrolyl)benzoic acid | 3,5-bis(2,5-dioxopyrrol-1-yl)benzoic acid | 3,5-bis[2,5-bis(oxidanylidene)pyrrol-1-yl]benzoic acid | 3,5-dimaleimidobenzoic acid | MLS002608658 | SMR001527404 | cid_239577 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H8N2O6 |
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| Mol. Mass. | 312.2338 |
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| SMILES | OC(=O)c1cc(cc(c1)N1C(=O)C=CC1=O)N1C(=O)C=CC1=O |c:13,21| |
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| Structure | 
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