Reaction Details |
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Target | Transthyretin |
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Ligand | BDBM50308499 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription |
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EC50 | >167158±n/a nM |
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Citation | PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay(2014)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Transthyretin |
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Name: | Transthyretin |
Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
Type: | Enzyme |
Mol. Mass.: | 15884.31 |
Organism: | Homo sapiens (Human) |
Description: | P02766 |
Residue: | 147 |
Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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BDBM50308499 |
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n/a |
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Name | BDBM50308499 |
Synonyms: | CHEMBL602722 | Ethyl 5-(4-chlorobenzoyl)-4-phenylthiazol-2-ylcarbamate | cid_7315332 |
Type | Small organic molecule |
Emp. Form. | C19H15ClN2O3S |
Mol. Mass. | 386.852 |
SMILES | CCOC(=O)Nc1nc(c(s1)C(=O)c1ccc(Cl)cc1)-c1ccccc1 |
Structure |
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