| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
|---|
| Ligand | BDBM129589 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Receptor Binding Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 277.15±n/a K |
|---|
| Ki | 2±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Quattropani, A; Baker-Glenn, C; Blackaby, W; Knight, C Pyrazole oxadiazole derivatives as S1P1 agonists US Patent US8802663 Publication Date 8/12/2014 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sphingosine 1-phosphate receptor 1 |
|---|
| Name: | Sphingosine 1-phosphate receptor 1 |
|---|
| Synonyms: | CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42836.02 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21453 |
|---|
| Residue: | 382 |
|---|
| Sequence: | MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
|
|
|
|---|
| BDBM129589 |
|---|
| n/a |
|---|
| Name | BDBM129589 |
|---|
| Synonyms: | US8802663, 117 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26N4O3 |
|---|
| Mol. Mass. | 394.4668 |
|---|
| SMILES | OCc1ccc(cc1)-c1noc(n1)-c1cnn(C2CCCCC2)c1C1CCCO1 |
|---|
| Structure | 
|
|---|
Search and Browse
