| Reaction Details |
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 | Report a problem with these data |
| Target | Capsid scaffolding protein |
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| Ligand | BDBM130377 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Nuclear Magnetic Resonance (NMR) Assay |
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| pH | 8±n/a |
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| IC50 | 3.9e+4± 8e+3 nM |
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| Comments | extracted |
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| Citation |  Gable, JE; Lee, GM; Jaishankar, P; Hearn, BR; Waddling, CA; Renslo, AR; Craik, CS Broad-spectrum allosteric inhibition of herpesvirus proteases. Biochemistry53:4648-60 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Capsid scaffolding protein |
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| Name: | Capsid scaffolding protein |
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| Synonyms: | APNG | Assemblin | Assembly protein | Capsid protein P40 | Human cytomegalovirus protease (HCMV Pr) | Human herpes virus 5 capsid protein P40 | Protease precursor | SCAF_HCMVA | UL80 | pPR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73854.16 |
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| Organism: | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
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| Description: | ChEMBL_158958 |
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| Residue: | 708 |
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| Sequence: | MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLN
INHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWV
TQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRY
DKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVE
PPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASP
AVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGA
PVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDE
PPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARK
RLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASS
SPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGP
STAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE
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| BDBM130377 |
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| n/a |
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| Name | BDBM130377 |
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| Synonyms: | N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(cyclohexylmethyl)pyridine-2- carboxamide (3) |
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| Type | Small organic molecule |
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| Emp. Form. | C28H31N3O4S |
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| Mol. Mass. | 505.628 |
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| SMILES | CS(=O)(=O)NC(=O)c1ccc(NC(=O)c2cccc(CC3CCCCC3)n2)c(Cc2ccccc2)c1 |
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| Structure | 
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