| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI |
|---|
| Ligand | BDBM133657 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence Based Assay |
|---|
| pH | 6.5±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 11000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Gerusz, V; Escaich, S; Oxoby, M; Denis, A Heterocyclic acrylamides and their use as pharmaceuticals US Patent US8846711 Publication Date 9/30/2014 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI |
|---|
| Name: | Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI |
|---|
| Synonyms: | Enoyl-ACP Reductase (FabI) | Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI | FABI_STAAR | NADPH-dependent enoyl-ACP reductase | fabI | trans-2-enoyl-[acyl carrier protein] reductase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 27989.00 |
|---|
| Organism: | Staphylococcus aureus |
|---|
| Description: | Q6GI75 |
|---|
| Residue: | 256 |
|---|
| Sequence: | MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEA
HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDI
SSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGP
DNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSG
VTGENIHVDSGFHAIK
|
|
|
|---|
| BDBM133657 |
|---|
| n/a |
|---|
| Name | BDBM133657 |
|---|
| Synonyms: | US8846711, 1 | US9051321, 1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H15N3O2 |
|---|
| Mol. Mass. | 257.2878 |
|---|
| SMILES | O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
