Reaction Details |
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Target | Regulator of G-protein signaling 8 |
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Ligand | BDBM50384774 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibitory Assay |
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IC50 | 11000±n/a nM |
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Citation | Neubig, R; Blazer, L; Husbands, S; Larsen, S; Traynor, J Small molecule inhibitors of RGS proteins US Patent US8865750 Publication Date 10/21/2014 |
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More Info.: | Get all data from this article, Assay Method |
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Regulator of G-protein signaling 8 |
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Name: | Regulator of G-protein signaling 8 |
Synonyms: | RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8) |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 20925.80 |
Organism: | Homo sapiens (Human) |
Description: | gi_74355113 |
Residue: | 180 |
Sequence: | MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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BDBM50384774 |
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n/a |
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Name | BDBM50384774 |
Synonyms: | CHEMBL1917204 | US20230414581, Compound 6 |
Type | Small organic molecule |
Emp. Form. | C16H13FN2O2S |
Mol. Mass. | 316.35 |
SMILES | Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O |
Structure |
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