| Reaction Details |
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 | Report a problem with these data |
| Target | Transthyretin |
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| Ligand | BDBM138363 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FP Assay |
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| IC50 | 755±n/a nM |
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| Citation |  Graef, IA; Alhamadsheh, M Identification of stabilizers of multimeric proteins US Patent US8877795 Publication Date 11/4/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Transthyretin |
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| Name: | Transthyretin |
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| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15884.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P02766 |
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| Residue: | 147 |
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| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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| BDBM138363 |
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| n/a |
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| Name | BDBM138363 |
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| Synonyms: | US10278929, Compound Ro-41-0960 | US11337935, Compound Ro-41-0960 | US8877795, Ro 41-0960 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H8FNO5 |
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| Mol. Mass. | 277.2047 |
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| SMILES | Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)c1ccccc1F |
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| Structure | 
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