| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C zeta type |
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| Ligand | BDBM139486 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase-Glo End-Point Assay |
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| IC50 | 26000±n/a nM |
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| Citation |  Antonetti, DA; Titchenell, P Compounds, formulations, and methods of protein kinase C inhibition US Patent US8889672 Publication Date 11/18/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein kinase C zeta type |
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| Name: | Protein kinase C zeta type |
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| Synonyms: | KPCZ_HUMAN | PKC2 | PRKCZ | Protein Kinase C, zeta | Protein kinase C (PKC) | Protein kinase C iota type/zeta type | Protein kinase C zeta | Protein kinase C zeta (PKCζ) | Protein kinase C zeta type | Protein kinase C zeta type (PKC zeta) | Protein kinase C zeta type (PKCzeta) | nPKC-zeta |
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| Type: | Enzyme |
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| Mol. Mass.: | 67649.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 592 |
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| Sequence: | MPSRTGPKMEGSGGRVRLKAHYGGDIFITSVDAATTFEELCEEVRDMCRLHQQHPLTLKW
VDSEGDPCTVSSQMELEEAFRLARQCRDEGLIIHVFPSTPEQPGLPCPGEDKSIYRRGAR
RWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC
RKHMDSVMPSQEPPVDDKNEDADLPSEETDGIAYISSSRKHDSIKDDSEDLKPVIDGMDG
IKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTE
KHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEI
CIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAP
EILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRF
LSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQIT
DDYGLDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYINPLLLSTEESV
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| BDBM139486 |
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| n/a |
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| Name | BDBM139486 |
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| Synonyms: | US8889672, 5132573 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12FNO2S |
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| Mol. Mass. | 265.303 |
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| SMILES | CCOC(=O)c1c(N)scc1-c1ccc(F)cc1 |
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| Structure | 
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