| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM103792 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | cAMP assays |
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| Temperature | 298.15±n/a K |
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| EC50 | 1.00±n/a nM |
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| Comments | extracted |
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| Citation |  Hughes, AD; Byun, D; Chen, Y; Fleury, M; Jacobsen, JR; Stangeland, EL; Wilson, RD; Yen, R Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity US Patent US9682957 Publication Date 6/20/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM103792 |
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| n/a |
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| Name | BDBM103792 |
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| Synonyms: | US8551978, I-62 | US8816088, I-62 | US9394275, I-62 | US9572802, Compound I-62 | US9682957, I-62 |
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| Type | Small organic molecule |
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| Emp. Form. | C49H52N6O7 |
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| Mol. Mass. | 836.9732 |
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| SMILES | CN(C(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)c1cccc(CC(=O)Nc2cccc(CCNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)c2)c1 |r| |
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| Structure | 
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