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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM141349 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 0.86±n/a nM | ||
| Citation |  Hayashi, K; Tamura, Y; Omori, N 5-membered ring heteroaromatic derivatives having NPY Y5 receptor antagonistic activity US Patent US8916594 Publication Date 12/23/2014 | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
| ||
| BDBM141349 | |||
| n/a | |||
| Name | BDBM141349 | ||
| Synonyms: | US8916594, I-029 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H22F2N4O3S | ||
| Mol. Mass. | 400.443 | ||
| SMILES | CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1ccc(F)c(F)c1 |r,wU:7.6,wD:10.13,(-10.27,.87,;-8.93,.1,;-7.6,.87,;-8.37,2.21,;-6.83,2.21,;-6.27,.1,;-4.93,.87,;-3.6,.1,;-2.26,.87,;-.93,.1,;-.93,-1.44,;-2.26,-2.21,;-3.6,-1.44,;.4,-2.21,;1.74,-1.44,;3.2,-1.91,;4.11,-.67,;3.2,.58,;1.74,.1,;5.65,-.67,;6.42,-2,;7.96,-2,;8.73,-.67,;10.27,-.67,;7.96,.67,;8.73,2,;6.42,.67,)| | ||
| Structure | 
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