Ki Summary

Reaction Details

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Target

D(3) dopamine receptor

Ligand

BDBM141832

Substrate/Competitor

n/a

Meas. Tech.

Radioligand Binding Assay

1.66±n/a nM

Citation

Rodriguez Sarmiento, RM; Wichmann, J Benzofurane-piperidine compounds US Patent US8921397 Publication Date 12/30/2014

More Info.:

Get all data from this article, Assay Method

D(3) dopamine receptor

Name:

D(3) dopamine receptor

Synonyms:

Type:

n/a

Mol. Mass.:

44243.43

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

400

Sequence:

MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC

BDBM141832

n/a

Name

BDBM141832

Synonyms:

US8921397, 74

Type

Small organic molecule

Emp. Form.

C30H36N2O4

Mol. Mass.

488.6178

SMILES

O=C(Cc1ccc2OCOc2c1)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 |r,wU:16.18,wD:13.14,(4.77,3.24,;5.54,1.91,;7.08,1.91,;7.85,.57,;7.08,-.76,;7.85,-2.09,;9.39,-2.09,;10.42,-3.24,;11.83,-2.61,;11.67,-1.08,;10.16,-.76,;9.39,.57,;4.77,.57,;3.23,.57,;2.46,1.91,;.92,1.91,;.15,.57,;-1.39,.57,;-2.16,-.76,;-3.7,-.76,;-4.47,.57,;-6.01,.57,;-6.78,-.76,;-6.01,-2.09,;-4.47,-2.09,;-8.32,-.76,;-9.22,-2.01,;-10.69,-1.53,;-10.69,.01,;-11.83,1.04,;-11.51,2.55,;-10.05,3.02,;-8.9,1.99,;-9.22,.48,;.92,-.76,;2.46,-.76,)|

Structure