| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-4 |
|---|
| Ligand | BDBM50397942 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Radioligand Binding |
|---|
| Temperature | 294.15±n/a K |
|---|
| Ki | 1.5±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Mazurov, A; Miao, L; Xiao, Y Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloalkanes US Patent US8921410 Publication Date 12/30/2014 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuronal acetylcholine receptor subunit alpha-4 |
|---|
| Name: | Neuronal acetylcholine receptor subunit alpha-4 |
|---|
| Synonyms: | ACHA4_RAT | Acra4 | Cholinergic, Nicotinic Alpha4Beta2 | Cholinergic, Nicotinic Alpha4Beta4 | Chrna4 | Neuronal acetylcholine receptor | Neuronal acetylcholine receptor (alpha4beta2 nAChR) | Neuronal acetylcholine receptor protein alpha-4 subunit | Neuronal acetylcholine receptor subunit alpha 4 beta 2 | Neuronal acetylcholine receptor subunit alpha-4 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 70196.44 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P09483 |
|---|
| Residue: | 630 |
|---|
| Sequence: | MANSGTGAPPPLLLLPLLLLLGTGLLPASSHIETRAHAEERLLKRLFSGYNKWSRPVANI
SDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGDYENVTSIRIPSELI
WRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK
FGSWTYDKAKIDLVSMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFI
IRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKVTLCISVLLSLTVFLLLITEIIPS
PTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPAWVRRVFLDIVPRLLF
MKRPSVVKDNCRRLIESMHKMANAPRFWPEPVGEPGILSDICNQGLSPAPTFCNPTDTAV
ETQPTCRSPPLEVPDLKTSEVEKASPCPSPGSCPPPKSSSGAPMLIKARSLSVQHVPSSQ
EAAEDGIRCRSRSIQYCVSQDGAASLADSKPTSSPTSLKARPSQLPVSDQASPCKCTCKE
PSPVSPVTVLKAGGTKAPPQHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAM
VIDRIFLWMFIIVCLLGTVGLFLPPWLAAC
|
|
|
|---|
| BDBM50397942 |
|---|
| n/a |
|---|
| Name | BDBM50397942 |
|---|
| Synonyms: | CHEMBL2179534 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H13BrN2O2 |
|---|
| Mol. Mass. | 285.137 |
|---|
| SMILES | Brc1ccoc1C(=O)N1CC2CNCC2C1 |
|---|
| Structure | 
|
|---|
Search and Browse
