| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-4 |
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| Ligand | BDBM50397942 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding |
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| Temperature | 294.15±n/a K |
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| Ki | 1.5±n/a nM |
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| Comments | extracted |
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| Citation |  Mazurov, A; Miao, L; Xiao, Y Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloalkanes US Patent US8921410 Publication Date 12/30/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Neuronal acetylcholine receptor subunit alpha-4 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-4 |
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| Synonyms: | ACHA4_HUMAN | CHRNA4 | CHRNA4 protein | NACRA4 | Neuronal acetylcholine receptor protein alpha-4 subunit | Neuronal acetylcholine receptor subunit alpha 4 beta 2 | Nicotinic acetylcholine receptor alpha4/beta2/alpha5 |
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| Type: | n/a |
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| Mol. Mass.: | 69963.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NACHRA4 |
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| Residue: | 627 |
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| Sequence: | MELGGPGAPRLLPPLLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISD
VVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWR
PDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG
SWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIR
RLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTS
LVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPTWVRRVFLDIVPRLLLMKR
PSVVKDNCRRLIESMHKMASAPRFWPEPEGEPPATSGTQSLHPPSPSFCVPLDVPAEPGP
SCKSPSDQLPPQQPLEAEKASPHPSPGPCRPPHGTQAPGLAKARSLSVQHMSSPGEAVEG
GVRCRSRSIQYCVPRDDAAPEADGQAAGALASRNTHSAELPPPDQPSPCKCTCKKEPSSV
SPSATVKTRSTKAPPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDR
IFLWMFIIVCLLGTVGLFLPPWLAGMI
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|
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| BDBM50397942 |
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| n/a |
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| Name | BDBM50397942 |
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| Synonyms: | CHEMBL2179534 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H13BrN2O2 |
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| Mol. Mass. | 285.137 |
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| SMILES | Brc1ccoc1C(=O)N1CC2CNCC2C1 |
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| Structure | 
|
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