| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 3 |
|---|
| Ligand | BDBM144576 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | EMSA Based Assay |
|---|
| IC50 | >1000000±n/a nM |
|---|
| Citation |  Turkson, J; Hamilton, AD Inhibitors of STAT3 US Patent US8969578 Publication Date 3/3/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Signal transducer and activator of transcription 3 |
|---|
| Name: | Signal transducer and activator of transcription 3 |
|---|
| Synonyms: | APRF | STAT3 | STAT3_HUMAN | Signal transducer and activator of transcription 3 | Signal transducer and activator of transcription 3 (STAT3) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 88064.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P40763 |
|---|
| Residue: | 770 |
|---|
| Sequence: | MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
|
|
|
|---|
| BDBM144576 |
|---|
| n/a |
|---|
| Name | BDBM144576 |
|---|
| Synonyms: | US8969578, 8 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H27N2O6P |
|---|
| Mol. Mass. | 458.444 |
|---|
| SMILES | CCCCCCNC(=O)c1nc(oc1Cc1ccc(OP(O)(O)=O)cc1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
