| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 2A1 |
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| Ligand | BDBM144806 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 870±n/a nM |
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| Comments | extracted |
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| Citation |  Schuster, VL; Chi, Y; Wasmuth, AS; Pottorf, RS; Olson, GL Prostaglandin transporter inhibitors and uses thereof US Patent US8952150 Publication Date 2/10/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 2A1 |
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| Name: | Solute carrier organic anion transporter family member 2A1 |
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| Synonyms: | Matr1 | Matrin F/G 1 | Prostaglandin transporter (PGT) | SO2A1_RAT | Slc21a2 | Slco2a1 | Solute carrier family 21 member 2 |
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| Type: | Protein |
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| Mol. Mass.: | 70404.97 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q00910 |
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| Residue: | 644 |
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| Sequence: | MGLLLKPGARQGSGTSSVPDRRCPRSVFSNIKVFVLCHGLLQLCQLLYSAYFKSSLTTIE
KRFGLSSSSSGLISSLNEISNATLIIFISYFGSRVNRPRMIGIGGLLLAAGAFVLTLPHF
LSEPYQYTSTTDGNRSSFQTDLCQKHFGALPPSKCHSTVPDTHKETSSLWGLMVVAQLLA
GIGTVPIQPFGISYVDDFAEPTNSPLYISILFAIAVFGPAFGYLLGSVMLRIFVDYGRVD
TATVNLSPGDPRWIGAWWLGLLISSGFLIVTSLPFFFFPRAMSRGAERSVTAEETMQTEE
DKSRGSLMDFIKRFPRIFLRLLMNPLFMLVVLSQCTFSSVIAGLSTFLNKFLEKQYGATA
AYANFLIGAVNLPAAALGMLFGGILMKRFVFPLQTIPRVAATIITISMILCVPLFFMGCS
TSAVAEVYPPSTSSSIHPQQPPACRRDCSCPDSFFHPVCGDNGVEYVSPCHAGCSSTNTS
SEASKEPIYLNCSCVSGGSASAKTGSCPTSCAQLLLPSIFLISFAALIACISHNPLYMMV
LRVVNQDEKSFAIGVQFLLMRLLAWLPAPSLYGLLIDSSCVRWNYLCSGRRGACAYYDND
ALRNRYLGLQMVYKALGTLLLFFISWRMKKNREYSLQENTSGLI
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| BDBM144806 |
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| n/a |
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| Name | BDBM144806 |
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| Synonyms: | US8952150, 86 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H42N8O5 |
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| Mol. Mass. | 738.8335 |
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| SMILES | Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3-c3ccccc3)n2)cc1 |
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| Structure | 
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