| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
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| Ligand | BDBM149708 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-Based Assay |
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| pH | 7.2±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 5±n/a nM |
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| Comments | extracted |
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| Citation |  Naganawa, A; Kusumi, K; Otsuki, K; Sekiguchi, T; Kakuuchi, A; Shinozaki, K; Yamamoto, H; Nonaka, S Phenyl derivative US Patent US8975409 Publication Date 3/10/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 2 |
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| Name: | Sphingosine 1-phosphate receptor 2 |
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| Synonyms: | Edg5 | S1PR2_RAT | S1pr2 | Sphingosine 1-phosphate receptor 2 (S1P2) |
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| Type: | Protein |
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| Mol. Mass.: | 38749.58 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P47752 |
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| Residue: | 352 |
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| Sequence: | MGGLYSEYLNPEKVQEHYNYTKETLDMQETPSRKVASAFIIILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGPVTLSLTPLQWFAREGSAFITLSASV
FSLLAIAIERQVAIAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLDHLEACS
TVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLG
VFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVL
RPLLCWRQGKGATGRRGGNPGHRLLPLRSSSSLERGLHMPTSPTFLEGNTVV
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| BDBM149708 |
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| n/a |
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| Name | BDBM149708 |
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| Synonyms: | US8975409, Example 15(6) |
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| Type | Small organic molecule |
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| Emp. Form. | C36H44FN3O6 |
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| Mol. Mass. | 633.7495 |
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| SMILES | CCC(CC)CC1(O)CCN(CC1)C(=O)Nc1cc(Oc2ccc(F)cc2)cc(Oc2ccc(cc2)C(=O)N2CCCC(O)C2)c1 |
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| Structure | 
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