| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM150204 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Dose-Displacement Binding Assay |
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| pH | 7.4±n/a |
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| Ki | 728.34±n/a nM |
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| Comments | extracted |
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| Citation |  Tafesse, L Pyridonemorphinan analogs and biological activity on opioid receptors US Patent US8980906 Publication Date 3/17/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
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|
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| BDBM150204 |
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| n/a |
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| Name | BDBM150204 |
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| Synonyms: | US8980906, 4 | US8980906, 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N3O4 |
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| Mol. Mass. | 435.5155 |
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| SMILES | COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(Cc5[nH]c(=O)c(cc5C[C@@]34O)C(N)=O)c2c1 |r| |
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| Structure | 
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