| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin B |
|---|
| Ligand | BDBM150782 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cathepsin Ezyme Assay |
|---|
| pH | 6±n/a |
|---|
| Ki | 41±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Singh, M; Raghav, N 2,3-Dihydroquinazolin-4(1H)-one derivatives as potential non-peptidyl inhibitors of cathepsins B and H. Bioorg Chem59:12-22 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin B |
|---|
| Name: | Cathepsin B |
|---|
| Synonyms: | n/a |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36777.57 |
|---|
| Organism: | Capra hircus (Goat) |
|---|
| Description: | n/a |
|---|
| Residue: | 335 |
|---|
| Sequence: | MWQLLATLSCLLVLTSARSSLHFPPLSDEMVNYVNKQNTTWKAGHNFYNVDLSYVKKLCG
AILGGPKLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSW
NTDWGDKGFFKILRGQDHCGIESEIVAGMPCTHQY
|
|
|
|---|
| BDBM150782 |
|---|
| n/a |
|---|
| Name | BDBM150782 |
|---|
| Synonyms: | 2-(4-Chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one (1e) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H11ClN2O |
|---|
| Mol. Mass. | 258.703 |
|---|
| SMILES | Clc1ccc(cc1)C1NC(=O)c2ccccc2N1 |
|---|
| Structure | 
|
|---|
Search and Browse
