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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine/threonine-protein kinase pim-1 | ||
| Ligand | BDBM151980 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | AlphaScreen Assay | ||
| IC50 | 0.02±n/a nM | ||
| Citation |  Burger, M; Drumm, III, JE; Nishiguchi, G; Rico, A; Simmons, RL; Taft, B; Tanner, H Ring-substituted N-pyridinyl amides as kinase inhibitors US Patent US8987457 Publication Date 3/24/2015 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine/threonine-protein kinase pim-1 | |||
| Name: | Serine/threonine-protein kinase pim-1 | ||
| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 35681.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P11309 | ||
| Residue: | 313 | ||
| Sequence: |
| ||
| BDBM151980 | |||
| n/a | |||
| Name | BDBM151980 | ||
| Synonyms: | US8987457, 174 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H26F3N7O3 | ||
| Mol. Mass. | 529.5142 | ||
| SMILES | COC(=O)N[C@H]1[C@@H](C)CN(C[C@H]1N)c1ccncc1NC(=O)c1nc(c(F)cc1N)-c1c(F)cccc1F |r,wU:6.6,11.12,5.4,(.67,4.23,;-.67,3.47,;-2,4.23,;-2,5.78,;-3.33,3.47,;-3.33,1.93,;-2,1.15,;-.67,1.93,;-2,-.38,;-3.33,-1.15,;-4.67,-.38,;-4.67,1.15,;-6,1.93,;-3.33,-2.69,;-4.67,-3.47,;-4.67,-5,;-3.33,-5.78,;-2,-5,;-2,-3.47,;-.67,-2.69,;.67,-3.47,;.67,-5,;2,-2.69,;2,-1.15,;3.33,-.38,;4.67,-1.15,;6,-.38,;4.67,-2.69,;3.33,-3.46,;3.33,-5,;3.33,1.15,;2,1.93,;.67,1.15,;2,3.47,;3.33,4.23,;4.67,3.47,;4.67,1.93,;6,1.15,)| | ||
| Structure | 
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