| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 12 |
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| Ligand | BDBM152026 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 18±n/a nM |
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| Citation |  Nagai, K; Nagasawa, K; Takahashi, H; Baba, M; Fujioka, S; Kondoh, E; Tanaka, K; Itoh, Y Ring-fused compound US Patent US8987473 Publication Date 3/24/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 12 |
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| Name: | Solute carrier family 22 member 12 |
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| Synonyms: | OATL4 | Organic anion transporter 4-like protein | RST | Renal-specific transporter | S22AC_HUMAN | SLC22A12 | Solute carrier family 22 member 12 | Solute carrier family 22 member 12 (URAT1) | URAT1 | Urate anion exchanger 1 | Urate anion exchanger 1 (URAT1) | Uric Acid Transporter 1 (URAT1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 59638.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96S37 |
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| Residue: | 553 |
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| Sequence: | MAFSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQ
ASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGW
VYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSY
LQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLG
FSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELW
RVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAF
GFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCI
LANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGA
ILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVKKATH
GTLGNSVLKSTQF
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| BDBM152026 |
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| n/a |
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| Name | BDBM152026 |
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| Synonyms: | US8987473, 97 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14Cl2N2O2 |
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| Mol. Mass. | 349.211 |
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| SMILES | Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CC(O)=O)ccc12 |
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| Structure | 
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