Reaction Details |
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Target | Fatty acid-binding protein, intestinal |
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Ligand | BDBM50085042 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ITC Titration |
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pH | 8±0 |
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Temperature | 310.15±0 K |
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Kd | 4.41e+3± 9.9e+2 nM |
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Citation | Patil, R; Laguerre, A; Wielens, J; Headey, SJ; Williams, ML; Hughes, ML; Mohanty, B; Porter, CJ; Scanlon, MJ Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein. ACS Chem Biol9:2526-34 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Fatty acid-binding protein, intestinal |
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Name: | Fatty acid-binding protein, intestinal |
Synonyms: | FABP2 | FABPI | FABPI_HUMAN | Fatty acid binding protein intestinal | Fatty acid-binding protein, intestinal | I-FABP | Intestinal fatty acid-binding protein (hIFABP) |
Type: | Protein |
Mol. Mass.: | 15207.56 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 132 |
Sequence: | MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIE
VVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVY
EGVEAKRIFKKD
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BDBM50085042 |
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n/a |
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Name | BDBM50085042 |
Synonyms: | 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester | CHEMBL672 | FENOFIBRATE | FNF | Fenofibric acid | Finofibrate | Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate | Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate | Lipantil (TN) | Procetofen | Tricor (TN) | propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate |
Type | Small organic molecule |
Emp. Form. | C20H21ClO4 |
Mol. Mass. | 360.831 |
SMILES | CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1 |
Structure |
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