| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI |
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| Ligand | BDBM133672 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Based Assay |
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| pH | 6.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 930±n/a nM |
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| Comments | extracted |
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| Citation |  Gerusz, V; Escaich, S; Oxoby, M; Denis, A Heterocyclic acrylamides and their use as pharmaceuticals US Patent US9051321 Publication Date 6/9/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI |
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| Name: | Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI |
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| Synonyms: | Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI | Enoyl-acyl carrier protein reductase (FaBI) | FABI_STAA8 | NADPH-dependent enoyl-ACP reductase (FabI) | fabI |
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| Type: | Enzyme |
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| Mol. Mass.: | 28019.03 |
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| Organism: | Staphylococcus aureus |
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| Description: | Q2FZQ3 |
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| Residue: | 256 |
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| Sequence: | MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEA
HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDI
SSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGP
DNIRVNAISASPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSG
VTGENIHVDSGFHAIK
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|
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| BDBM133672 |
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| n/a |
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| Name | BDBM133672 |
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| Synonyms: | US8846711, 16 | US9051321, 16 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N4O3 |
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| Mol. Mass. | 364.3978 |
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| SMILES | O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCC(C1)Oc1cccnc1 |
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| Structure | 
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