| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Ligand | BDBM166409 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 8±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 3.1±n/a nM |
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| Comments | extracted |
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| Citation |  Takashima, H; Tsuruta, R; Yabuuchi, T; Oka, Y; Urabe, H; Suga, Y; Takahashi, M; Uneuchi, F; Kotsubo, H; Shoji, M; Kawaguchi, Y Hydroxamic acid derivative US Patent US9073821 Publication Date 7/7/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Name: | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Synonyms: | LPXC_PSEAE | Protein envA | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC) | UDP-3-O-acyl-GlcNAc deacetylase | UDP-3-O-acyl-GlcNAc deacetylase (LpxC) | envA | lpxC |
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| Type: | Enzyme |
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| Mol. Mass.: | 33428.15 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | P47205 |
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| Residue: | 303 |
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| Sequence: | MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGET
TMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQ
EQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTS
FVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKIL
DAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRPA
AAV
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| BDBM166409 |
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| n/a |
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| Name | BDBM166409 |
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| Synonyms: | US9073821, 211 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N3O5 |
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| Mol. Mass. | 385.4137 |
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| SMILES | CCOc1ccc(cc1)-c1ccc(cc1)C(=O)N(C)C(C(=O)NC)C(=O)NO |
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| Structure | 
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