| Reaction Details |
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 | Report a problem with these data |
| Target | Arachidonate 5-lipoxygenase-activating protein |
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| Ligand | BDBM167014 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Homogeneous Time Resolved Fluorescence Assay |
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| Ki | 1±n/a nM |
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| Citation |  Eccles, W; Fitzgerald, AE; Hack, MD; Hawryluk, NA; Jones, WM; Keith, JM; Krawczuk, P; Lebsack, AD; Liu, J; Mani, NS; McClure, KJ; Meduna, SP; Rosen, MD Flap modulators US Patent US9073876 Publication Date 7/7/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Arachidonate 5-lipoxygenase-activating protein |
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| Name: | Arachidonate 5-lipoxygenase-activating protein |
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| Synonyms: | 5-lipoxygenase activating protein | 5-lipoxygenase-activating protein (FLAP) | 5-lipoxygenase/FLAP | AL5AP_HUMAN | ALOX5AP | FLAP | MK-886-binding protein |
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| Type: | Enzyme |
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| Mol. Mass.: | 18159.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P20292 |
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| Residue: | 161 |
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| Sequence: | MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
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| BDBM167014 |
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| n/a |
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| Name | BDBM167014 |
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| Synonyms: | US9073876, 100 | US9732093, Compound 100 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19FN6O2 |
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| Mol. Mass. | 382.3916 |
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| SMILES | COc1nc(N)cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)n1 |
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| Structure | 
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